FGF-1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-317-10ug | 10ug | £373.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Fibroblast Growth Factor 1, Acidic Fibroblast Growth Factor, Endothelial Cell Growth Factor, ECGF, Heparin-binding Growth Factor 1, HBGF-1
Application Note:
This recombinant proteins is for research use only.
Background:
Fibroblast growth factors (FGFs) constitute a family of heparin-binding polypeptides involved in the regulation of biological responses such as growth, differentiation and angiogenesis. The biological effects of FGFs are mediated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3 and FGFR4. FGF-1 [FGF-acidic; ECGF; HBGF-1] is a powerful mitogen of cells of mesodermal, ectodermal and endodermal origin. FGF-1 association with heparan sulfate is a prerequisite for activation of FGF receptors. FGF-1 plays a role in various stages of development and morphogenesis as well as in angiogenesis and wound healing processes. Recent data indicate a role of FGF-1 in inflammation and obesity. FGF-1 is selectively induced in fat cells by high-fat diet feeding and established the PPARgamma-FGF-1 axis as a critical pathway that regulates adipose tissue remodeling.
Buffer:
In PBS containing 0.2 mM DTT. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Fusion Tag:
Tag Free
NCBI Gene ID #:
2246
NCBI Official Name:
fibroblast growth factor 1 (acidic)
NCBI Official Symbol:
FGF1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
P05230
Protein GI Number:
122737
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q04206