Calreticulin Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-137-10ug | 10ug | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Working aliquots are stable for up to 3 months when stored at -20˚C.
Documents
Further Information
Additional Names:
CRP55, Calregulin, Endoplasmic Reticulum Resident Protein 60, ERp60, grp60
Application Note:
This recombinant proteins is for research use only.
Background:
Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ?calreticulin/calnexin cycle? that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule. Recently, Calreticulin was shown to enhance the merger of macrophages and tumor cells, increasing phagocytosis.
Buffer:
0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl.
Concentration:
0.3mg/ml
Fusion Tag:
His Tag
NCBI Gene ID #:
811
NCBI Official Name:
calreticulin
NCBI Official Symbol:
CALR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P27797
Protein GI Number:
4757900
Purity:
>90% (SDS-PAGE).
Endotoxin level is less than 1EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
O00548