Jagged-1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-085-50ug | 50ug | £686.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Working aliquots are stable for up to 3 months when stored at -20˚C.
Documents
Further Information
Additional Names:
Protein Jagged-1, hJ1, CD339, JAG1
Application Note:
This recombinant proteins is for research use only.
Background:
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
Biological Activity:
Inhibits adipogenesis of mesenchymal stem cells (MSCs). Induces Hes-1 in 3T3L-1 cells.
Buffer:
0.2um-filtered solution in PBS.
Concentration:
0.5mg/ml
Fusion Tag:
Fc Tag
NCBI Gene ID #:
182
NCBI Official Name:
jagged 1
NCBI Official Symbol:
JAG1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P78504
Protein GI Number:
4557679
Purity:
>90% (SDS-PAGE).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O00548