IL-1 Receptor Type I Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-235-50ug | 50ug | £577.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
IL-1 Receptor Type I, Interleukin-1 Receptor Type I, RI, Interleukin-1 Receptor alpha CD121a, CD121 Antigen-like Family Member A
Application Note:
This recombinant proteins is for research use only.
Background:
IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
Biological Activity:
Blocks IL-1beta activity.
Buffer:
Contains PBS. Reconstitute with 50 μl sterile water.
Concentration:
1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
3554
NCBI Official Name:
interleukin 1 receptor, type I
NCBI Official Symbol:
IL1R1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
P14778
Protein GI Number:
124308
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P43488