DLL4 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-076-10ug | 10ug | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Delta-like Protein 4, Delta4
Application Note:
This recombinant proteins is for research use only.
Background:
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
Biological Activity:
Inhibits adipogenesis of 3T3L-1 cells and mesenchymal stem cells (MSCs). Induces Hes-1 in 3T3L-1 cells.
Buffer:
Contains PBS + 0.5 % Trehalose. Reconstitute with 100 μl sterile water.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
54567
NCBI Official Name:
delta-like 4 (Drosophila)
NCBI Official Symbol:
DLL4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
Q9NR61
Protein GI Number:
13431490
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9Y5C1