Annexin V ATTO 488 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-219-100tests | 100tests | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Stable for at least 1 year after receipt when stored at +4˚C.
Documents
Further Information
Additional Names:
Annexin A5, Endonexin II, Lipocortin V, Placental Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha
Application Note:
This recombinant proteins is for research use only.
Background:
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e. g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
Buffer:
In PBS, pH 7.4, containing 0.02% sodium azide.
Fusion Tag:
GST tag
NCBI Gene ID #:
308
NCBI Official Name:
annexin A5
NCBI Official Symbol:
ANXA5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P08758
Protein GI Number:
113960
Purity:
>95% (SDS-PAGE)
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P08758