IL-6 non-lytic Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-483-50ug | 50ug | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
Documents
Further Information
Additional Names:
Interleukin-6, B Cell Stimulatory Factor 2, BSF-2, CTL Differentiation Factor, CDF, Interferon beta2, IFN-beta2
Application Note:
This recombinant proteins is for research use only.
Background:
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
Biological Activity:
Shows the biological function of the IL-6 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μl sterile water. Add 1X PBS to the desired protein concentration.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
3569
NCBI Official Name:
interleukin 6
NCBI Official Symbol:
IL6
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000591
Protein GI Number:
10834984
Purity:
>98% (SDS-PAGE).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
Q01638