PFKFB1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-350-0.05mg | 0.05mg | £883.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1, 6PF-2-K/Fru-2, 6-P2ase liver isozyme, Fructose-2, 6-bisphosphatase, PFKFB1, F6PK, PFRX, PFK, FBPase 1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
5207
NCBI Official Name:
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
NCBI Official Symbol:
PFKFB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
55.6 kD
Protein Accession #:
P16118
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P16118