INPP5A Recombinant Protein

ProSci
Product Code: PSI-92-354
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-92-354-0.05mg0.05mg£883.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
Type I inositol 1, 4, 5-trisphosphate 5-phosphatase, INPP5A, 5PTase
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
3632
NCBI Official Name:
inositol polyphosphate-5-phosphatase A
NCBI Official Symbol:
INPP5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
48.5 kD
Protein Accession #:
Q14642
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q14642