6-phosphogluconate dehydrogenase Recombinant Protein

ProSci
Product Code: PSI-92-379
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-92-379-0.05mg0.05mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
6-phosphogluconate dehydrogenase, decarboxylating, PGD, PGDH, 6PGD
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein, and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency, an autosomal hereditary disease effecting the red blood cells.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
5226
NCBI Official Name:
phosphogluconate dehydrogenase
NCBI Official Symbol:
PGD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
54.2 kD
Protein Accession #:
P52209
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P52209