Irisin:Fc Recombinant Protein

ProSci
Product Code: PSI-90-296
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-90-296-10ug10ug£469.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species:
  • Human
  • Monkey
  • Mouse
  • Rat
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.

Documents

Further Information

Additional Names:
Fibronectin Type III Domain-containing Protein 5 (cleaved), Fibronectin Type III Repeat-containing Protein 2 (cleaved), FNDC5 (cleaved)
Application Note:
This recombinant proteins is for research use only.
Background:
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Buffer:
Contains PBS. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
252995
NCBI Official Name:
fibronectin type III domain containing 5
NCBI Official Symbol:
FNDC5
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
Q8NAU1
Protein GI Number:
403314395
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q14457