Angiopoietin-2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-311-10ug | 10ug | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Ang-2, Ang2, Angpt2, Agpt2
Application Note:
This recombinant proteins is for research use only.
Background:
Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.
Buffer:
Contains PBS with trehalose and Brij35. Reconstitute with 100 μl sterile water.
Concentration:
0.1 mg /ml after reconstitution.
Fusion Tag:
DDDDK Tag
NCBI Gene ID #:
11601
NCBI Official Name:
angiopoietin 2
NCBI Official Symbol:
Angpt2
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
O35608
Protein GI Number:
46577675
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.05EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.05EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P09874