FasL Soluble Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-312-10ug | 10ug | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
APO-1L, CD95L, CD178, TNFSF6, Fas Ligand
Application Note:
This recombinant proteins is for research use only.
Background:
Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.
Biological Activity:
Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml.
Buffer:
Contains PBS. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
356
NCBI Official Name:
Fas ligand (TNF superfamily, member 6)
NCBI Official Symbol:
FASLG
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
P48023
Protein GI Number:
4557329
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O88554