FasL, Soluble Recombinant Protein

ProSci
Product Code: PSI-90-215
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-90-215-10ug10ug£469.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.

Documents

Further Information

Additional Names:
APO-1L, CD95L, CD178, TNFSF6, Fas Ligand
Application Note:
This recombinant proteins is for research use only.
Background:
FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis and in T cell development.
Biological Activity:
Induces apoptosis of human Jurkat T cells at a concentration of <1ng/ml in the presence of 0.1 to 1ug/ml TNF Ligands Enhancer (Prod. No. AG-35B-0001). In the absence of TNF Ligands Enhancer, FasL is working at 50-100 fold higher concentrations.
Buffer:
Contains PBS. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Fusion Tag:
DDDDK Tag
NCBI Gene ID #:
356
NCBI Official Name:
Fas ligand (TNF superfamily, member 6)
NCBI Official Symbol:
FASLG
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
P48023
Protein GI Number:
4557329
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.05EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O35714