LAG-3 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-246-50ug | 50ug | £673.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Storage:
Stable for at least 6 months after receipt when stored at +4˚C.
Documents
Further Information
Additional Names:
Lymphocyte Activation Gene-3, FDC Protein, CD223
Application Note:
This recombinant proteins is for research use only.
Background:
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Biological Activity:
Induces maturation of mouse dendritic cells in vitro. Induces CD4 and CD8 antigen-specific T cells responses when coinjected s.c. in mice, together with the antigen.
Buffer:
In PBS.
Concentration:
0.5 mg/ml
Fusion Tag:
Fc Tag
NCBI Gene ID #:
16768
NCBI Official Name:
lymphocyte-activation gene 3?
NCBI Official Symbol:
LAG3
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
Q61790
Protein GI Number:
2497295
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
P55036