Fn14 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-242-50ug | 50ug | £541.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Tumor Necrosis Factor Receptor Superfamily Member 12A, FGF-inducible 14, Tweak-receptor, CD266, TNFRSF12A
Application Note:
This recombinant proteins is for research use only.
Background:
TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK?Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.
Buffer:
Contains PBS. Reconstitute with 50 μl sterile water.
Concentration:
1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
51330
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 12A
NCBI Official Symbol:
TNFRSF12A
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
Q9NP84
Protein GI Number:
7706186
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q2YEJ4