DLK1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-112-10ug | 10ug | £541.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1
Application Note:
This recombinant proteins is for research use only.
Background:
The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
Biological Activity:
Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells.
Buffer:
Contains PBS + 0.02% CHAPS. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
13386
NCBI Official Name:
delta-like 1 homolog (Drosophila)
NCBI Official Symbol:
Dlk1
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
Q09163
Protein GI Number:
1169354
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q6IA17