Notch1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-291-50ug | 50ug | £577.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300
Application Note:
This recombinant proteins is for research use only.
Background:
Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
Buffer:
Contains PBS. Reconstitute with 50 μl sterile water.
Concentration:
1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
18128
NCBI Official Name:
notch 1
NCBI Official Symbol:
Notch1
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
Q01705
Protein GI Number:
384872684
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
P48023