CREB-binding Protein highly active Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-344-2ug | 2ug | £522.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Shipping:
Dry ice
Storage:
Stable for at least 6 months after receipt when stored at -80˚C.
Documents
Further Information
Additional Names:
CBP, CREBBP
Application Note:
This recombinant proteins is for research use only.
Background:
CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.
Biological Activity:
~50-100ng are required for standard HAT assay.
Buffer:
In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50-100mM imidazole and 10% glycerol.
Concentration:
Lot dependent (0.2-0.5mg/ml)
Fusion Tag:
His Tag
NCBI Gene ID #:
12914
NCBI Official Name:
CREB binding protein
NCBI Official Symbol:
Crebbp
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P45481
Protein GI Number:
341940549
Purity:
>95% (SDS-PAGE)
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Sf21 cells
Swissprot #:
O88430