DLL4 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-154-10ug | 10ug | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
Working aliquots are stable for up to 3 months when stored at -20˚C.
Documents
Further Information
Additional Names:
Delta-like Protein 4, Delta4
Application Note:
This recombinant proteins is for research use only.
Background:
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
Biological Activity:
Inhibits adipogenesis of 3T3L-1 cells.
Buffer:
0.2um-filtered solution in PBS.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
54485
NCBI Official Name:
delta-like 4 (Drosophila)
NCBI Official Symbol:
Dll4
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
Q9JI71
Protein GI Number:
341940447
Purity:
>90% (SDS-PAGE).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P80370