IL-4 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-480-10ug | 10ug | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
Documents
Further Information
Additional Names:
Interleukin-4, B Cell Stimulatory Factor 1, BSF-1
Application Note:
This recombinant proteins is for research use only.
Background:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1 and IL-6 by macrophages.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS (pH 7.4). Reconstituted in sterile H2O not less than 100 μg/ml, which can then be further diluted in other aqueous solutions.
Fusion Tag:
His Tag
NCBI Gene ID #:
16189
NCBI Official Name:
interleukin 4
NCBI Official Symbol:
Il4
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_067258
Protein GI Number:
10946584
Purity:
>98% (SDS-PAGE).
Endotoxin level is less than 0.1EU/ μg protein (LAL test; Lonza).
Endotoxin level is less than 0.1EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q14213