CD278 [ICOS] Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-446-100ug | 100ug | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
Documents
Further Information
Additional Names:
ICOS, Inducible T Cell Costimulator, CRP1, CD28-related Protein-1, AILIM
Application Note:
This recombinant proteins is for research use only.
Background:
CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μg/ml in sterile PBS.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
54167
NCBI Official Name:
inducible T cell co-stimulator
NCBI Official Symbol:
Icos
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_059508
Protein GI Number:
224809335
Purity:
>98% (SDS-PAGE).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
P22301