IL-2 Recombinant Protein

ProSci
Product Code: PSI-90-467
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-90-467-50ug50ug£597.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Mouse
Storage:
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.

Documents

Further Information

Additional Names:
Interleukin-2, Aldesleukin
Application Note:
This recombinant proteins is for research use only.
Background:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μg/ml in sterile PBS.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
16183
NCBI Official Name:
interleukin 2
NCBI Official Symbol:
Il2
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_032392
Protein GI Number:
7110653
Purity:
>98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
Q9GZX6