CNDP dipeptidase 2 Recombinant Protein

ProSci
Product Code: PSI-92-416
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-92-416-0.05mg0.05mg£673.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Mouse
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
CNDP2/CNDP dipeptidase 2/Cytosolic non-specific dipeptidase/Glutamate carboxypeptidase-like protein 1/Cn2, CNDP2, CPGL
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Mouse cytosolic non-specific dipeptidase(CNDP2) is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 has 2 Isoform: Isoform 1 is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 hydrolyzes a variety of dipeptides including L-carnosine and has a strong preference for Cys-Gly. It is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis. It may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl,10% Glycerol, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
66054
NCBI Official Name:
CNDP dipeptidase 2 (metallopeptidase M20 family)
NCBI Official Symbol:
Cndp2
NCBI Organism:
Mus musculus
Physical State:
Liquid
Predicted Molecular Weight:
53.8 kD
Protein Accession #:
Q9D1A2
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q9D1A2