IL-2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-470-10ug | 10ug | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Rat
Storage:
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
Documents
Further Information
Additional Names:
Interleukin-2, Aldesleukin
Application Note:
This recombinant proteins is for research use only.
Background:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS (pH 7.4). Reconstituted in sterile H2O not less than 100 μg/ml, which can then be further diluted in other aqueous solutions.
Fusion Tag:
His Tag
NCBI Gene ID #:
116562
NCBI Official Name:
interleukin 2
NCBI Official Symbol:
Il2
NCBI Organism:
Rattus norvegicus
Physical State:
Lyophilized
Protein Accession #:
NP_446288
Protein GI Number:
16758692
Purity:
>95% (SDS-PAGE).
Endotoxin level is less than 1EU/ μg protein (LAL test; Lonza).
Endotoxin level is less than 1EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9GZX6