Gankyrin Recombinant Protein
| Code | Size | Price |
|---|
| PSI-91-146-0.05mg | 0.05mg | £673.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
26S Proteasome Non-ATPase Regulatory Subunit 10, 26S Proteasome Regulatory Subunit p28, Gankyrin, p28(GANK), PSMD10
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 10% Glycerol, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
Tag Free
NCBI Gene ID #:
5716
NCBI Official Name:
proteasome 26S subunit, non-ATPase 10
NCBI Official Symbol:
PSMD10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
24.43 kD
Protein Accession #:
O75832
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
O75832