UCH-L3 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-91-169-0.05mg | 0.05mg | £818.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L3, UCH-L3, Ubiquitin Thioesterase L3, UCHL3
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Ubiquitin Carboxyl-Terminal Hydrolases (UCHs) are a family of cysteine hydrolases. They catalyze the hydrolysis of amides, thioesters and esters, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin. Up regulation of UCHL3 is associated with uterine cervical neoplasms. UCHL3 is implicated in age related cognitive disorders. UCHL3 also promotes adipogenesis and insulin signaling. In mice, UCHL3 knockout have been shown to be resistant to diet-induced obesity.
Buffer:
Supplied as a 0.2 um filtered solution of 50mM TrisHCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
7347
NCBI Official Name:
ubiquitin C-terminal hydrolase L3
NCBI Official Symbol:
UCHL3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
27.25 kD
Protein Accession #:
P15374
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P15374