Autophagy protein 5 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-187-0.05mg | 0.05mg | £673.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
Autophagy protein 5, APG5-like, Apoptosis-specific protein, APG5L, ASP, ATG5
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM Tris,0.2M NaCl,1mM DTT,40%glycerol, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
Tag Free
NCBI Gene ID #:
9474
NCBI Official Name:
autophagy related 5
NCBI Official Symbol:
ATG5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
32.4 kD
Protein Accession #:
Q9H1Y0
Protein GI Number:
530379522
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9H1Y0