Sentrin-specific protease 2 Recombinant Protein

ProSci
Product Code: PSI-92-222
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-92-222-0.05mg0.05mg£389.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2., SENP2
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
Buffer:
Supplied as a 0.2 um filtered solution of 50mM HEPES,5% glycerol pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His, SUMO tag
NCBI Gene ID #:
59343
NCBI Official Name:
SUMO1/sentrin/SMT3 specific peptidase 2
NCBI Official Symbol:
SENP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
39.2 kD
Protein Accession #:
Q9HC62
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9HC62