IGF-I Recombinant Protein

Product Code: PSI-91-022

Supplier: ProSci

Code	Size	Price

PSI-91-022-0.05mg

0.05mg

£373.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Human

Storage:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Datasheet

Further Information

Additional Names:

Insulin-Like Growth Factor I, IGF-I, Mechano Growth Factor, MGF, Somatomedin-C, IGF1, IBP1, IGF-1

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.

Buffer:

Lyophilized from a 0.2 um filtered solution of 300mM NaAc, pH 6.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 500mM Acetic Acid.

Fusion Tag:

Tag Free

NCBI Gene ID #:

3479

NCBI Official Name:

insulin like growth factor 1

NCBI Official Symbol:

IGF1

NCBI Organism:

Homo sapiens

Physical State:

Lyophilized

Predicted Molecular Weight:

7.3 kD

Protein Accession #:

P05019

Protein GI Number:

767957252

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.05 ng/ug (0.5 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

E. coli

Swissprot #:

P05019