PKC epsilon Recombinant Protein

Product Code: PSI-91-145

Supplier: ProSci

Code	Size	Price

PSI-91-145-0.05mg

0.05mg

£673.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Human

Storage:

Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Datasheet

Further Information

Additional Names:

Protein Kinase C Epsilon Type, nPKC-Epsilon, PRKCE, PKCE

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Protein Kinase C Epsilon type is a member of the serine- and threonine-specific protein kinase family that can be activated by calcium and the second messenger diacylglycerol. Protein Kinase C Epsilon contains these domains: one AGC-kinase C-terminal domain, one C2 domain, one protein kinase domain and two phorbol-ester/DAG-type zinc fingers. Protein Kinase C Epsilon phosphorylate a variety of protein targets and has been identified to participate in diverse cellular signaling pathways. It has many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Protein Kinase C Epsilon also serves as the receptor for phorbol esters, a class of tumor promoters.

Buffer:

Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Fusion Tag:

C-6 His tag

NCBI Gene ID #:

5581

NCBI Official Name:

protein kinase C epsilon

NCBI Official Symbol:

PRKCE

NCBI Organism:

Homo sapiens

Physical State:

Liquid

Predicted Molecular Weight:

19.64 kD

Protein Accession #:

Q02156

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

E. coli

Swissprot #:

Q02156