UBE2C Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-139-0.05mg | 0.05mg | £673.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
Ubiquitin-Conjugating Enzyme E2 C, UbcH10, Ubiquitin Carrier Protein C, Ubiquitin-Protein Ligase C, UBE2C
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a 179 amino acid enzyme that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2C is highly expressed in tumor tissues and at low levels in most adult normal tissues. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C accepts Ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), which has E3 ubiquitin ligase activity, and targets for destruction substrates from the preceding mitosis (Cyclin A, Cyclin B, Securin, Geminin).
Buffer:
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH 7.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
11065
NCBI Official Name:
ubiquitin conjugating enzyme E2 C
NCBI Official Symbol:
UBE2C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
23.3 kD
Protein Accession #:
O00762
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
O00762