Carbonic anhydrase 14 Recombinant Protein

ProSci
Product Code: PSI-92-523
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-92-523-0.05mg0.05mg£883.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Mouse
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
Carbonic Anhydrase 14, Carbonate Dehydratase XIV, Carbonic Anhydrase XIV, CA-XIV, CA14
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Mouse Ca14,also known as Carbonic anhydrase 14,is a member of large family of zinc metalloenzymes .It could catalyze reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumors and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system
Buffer:
Supplied as a 0.2 um filtered solution of 20mM Tris,150mM NaCl,pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
23831
NCBI Official Name:
carbonic anhydrase 14
NCBI Official Symbol:
Car14
NCBI Organism:
Mus musculus
Physical State:
Liquid
Predicted Molecular Weight:
32.3 kD
Protein Accession #:
Q9WVT6
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9WVT6