IL-8 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-91-028-0.05mg | 0.05mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
Documents
Further Information
Additional Names:
Interleukin-8, IL-8, C-X-C Motif Chemokine 8, Emoctakin, Granulocyte Chemotactic Protein 1, GCP-1, Monocyte-Derived Neutrophil Chemotactic Factor, MDNCF, Monocyte-Derived Neutrophil-Activating Peptide, MONAP, Neutrophil-Activating Protein 1, NAP-1, Protein 3-10C, T-Cell Chemotactic Factor, IL8, CXCL8
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.
Biological Activity:
Recombinant IL-8 (3-79) is fully biologically active when compared to standards.
ED50 is less than 2 ng/ml as determined by its chemotaxis of hCXCR-2 transfected mouse BaF/3 cells.
Specific Activity of 5.0 x 105 IU/mg.
ED50 is less than 2 ng/ml as determined by its chemotaxis of hCXCR-2 transfected mouse BaF/3 cells.
Specific Activity of 5.0 x 105 IU/mg.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
Tag Free
NCBI Gene ID #:
3576
NCBI Official Name:
C-X-C motif chemokine ligand 8
NCBI Official Symbol:
CXCL8
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
8.9 kD
Protein Accession #:
P10145
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P10145