ProSci

IL-36 gamma Recombinant Protein

Product Code:
 
PSI-92-669
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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PSI-92-669-0.05mg0.05mg£838.00
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Further Information

Additional Names:
Interleukin-36 gamma, IL36G, IL-1-related protein 2, IL-1RP2, IL-1 epsilon, IL-1F9, Interleukin-1 homolog 1, IL-1H1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Interleukin-36 gamma (IL-36 gamma ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36 alpha, beta , and gamma , formerly known as IL-1F6, F8, and F9 respectively. IL-36 alpha has been detected in both neuronal and synovial tissue, whereas IL-36 beta and IL-36 gamma are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36 beta and IL-36 gamma stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36 alpha is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36 gamma plays an important role in communicating the cell death to surrounding cells.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM Tris,100mM Nacl,0.1mM EDTA,pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
Tag Free
NCBI Gene ID #:
6347
NCBI Official Name:
C-C motif chemokine ligand 2
NCBI Official Symbol:
CCL2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
17 kD
Protein Accession #:
P13500
Protein GI Number:
189054143
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P13500

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