TSLP Receptor Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-533-0.05mg | 0.05mg | £753.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
Documents
Further Information
Additional Names:
CRL2, CRLF2, CRLM-2, PCOR1, CRL2 cytokine receptor, CRL2 precusor, CRLF2Y, Cytokine receptor-like 2, cytokine receptor-like factor 2, ILXR, IL-XR, P2RY8/CRLF2 fusion, Thymic stromal lymphopoietin protein receptor, Thymic stromal-derived lymphopoietin receptor, TSLP receptor, TSLPR, TSP R
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
The cytokine thymic stromal lymphopoietin receptor (TSLPR) is consisting of a common gamma receptor?like chain (TSLPR- gamma ) and a common interleukin 7 (IL-7) R alpha chain that belongs to the type 1 cytokine receptor family. Transfection of TSLPR cDNA result in only low affinity binding, while cotransfection of the IL-7R alpha chain cDNA shows high affinity binding. TSLP and TSLPR play a critical role in the initiation of allergic diseases in mice. The TSLP R cDNA encodes a transmembrane receptor containing 370 amino acids (aa) with two potential N-linked glycosylation sites and a cytoplasmic domain of 104 aa including a single tyrosine residue. TSLPR can mediate signaling of the signal transducer and activator of transcription 5 (Stat5) by TSLP. TSLP R is broadly expressed in the immune and hematopoietic cells, particularly in hematopoietic progenitors and myeloid cells.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
C-Fc tag
NCBI Gene ID #:
57914
NCBI Official Name:
cytokine receptor-like factor 2
NCBI Official Symbol:
Crlf2
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
49.8 kD
Protein Accession #:
Q8CII9
Protein GI Number:
929654682
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q8CII9