GH receptor Recombinant Protein

Product Code: PSI-92-595

Supplier: ProSci

Code	Size	Price

PSI-92-595-0.05mg

0.05mg

£481.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Mouse

Storage:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Datasheet

Further Information

Additional Names:

Growth hormone receptor, Ghr, Growth Hormone R, GHBP

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

Buffer:

Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Fusion Tag:

C-Fc tag

NCBI Gene ID #:

14600

NCBI Official Name:

growth hormone receptor

NCBI Official Symbol:

Ghr

NCBI Organism:

Mus musculus

Physical State:

Lyophilized

Predicted Molecular Weight:

58.3 kD

Protein Accession #:

Q3UP14

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

Human Cells

Swissprot #:

Q3UP14