GRP Recombinant Protein

Product Code: PSI-91-210

Supplier: ProSci

Code	Size	Price

PSI-91-210-0.05mg

0.05mg

£838.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Human

Storage:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Datasheet

Further Information

Additional Names:

U6 snRNA-Associated Sm-Like Protein LSm4, Glycine-Rich Protein, GRP, LSM4

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which are essential during ribosomal subunit assembly.

Buffer:

Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Fusion Tag:

N-6 His tag

NCBI Gene ID #:

25804

NCBI Official Name:

LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated

NCBI Official Symbol:

LSM4

NCBI Organism:

Homo sapiens

Physical State:

Lyophilized

Predicted Molecular Weight:

17.5 kD

Protein Accession #:

Q9Y4Z0

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

E. coli

Swissprot #:

Q9Y4Z0