GDP-L-Fucose Synthase Recombinant Protein

ProSci
Product Code: PSI-91-969
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-91-969-0.05mg0.05mg£883.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
GDP-L-Fucose Synthase, GDP-4-Keto-6-Deoxy-D-Mannose-3, 5-Epimerase-4-Reductase, Protein FX, Red Cell NADP(H)-Binding Protein, Short-Chain Dehydrogenase/Reductase Family 4E Member 1, TSTA3, SDR4E1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
7264
NCBI Official Name:
tissue specific transplantation antigen P35B
NCBI Official Symbol:
TSTA3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
36.96 kD
Protein Accession #:
Q13630
Protein GI Number:
767904139
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q13630