Galactokinase Recombinant Protein

ProSci
Product Code: PSI-92-004
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-92-004-0.05mg0.05mg£883.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
Galactokinase, Galactose Kinase, GALK1, GALK
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus, a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose, which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II, an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of Galactitol in the lenses.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
2584
NCBI Official Name:
galactokinase 1
NCBI Official Symbol:
GALK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
43.3 kD
Protein Accession #:
P51570
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P51570