PTH Recombinant Protein
| Code | Size | Price |
|---|
| PSI-91-008-0.05mg | 0.05mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
Documents
Further Information
Additional Names:
Parathyroid Hormone, PTH, Parathormone, Parathyrin
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.
Biological Activity:
Recombinant PTH is fully biologically active when compared to standards.
Specific Activity of 1.0 x 104 IU/mg as calculated by the UMR106 cell/cAMP method.
Specific Activity of 1.0 x 104 IU/mg as calculated by the UMR106 cell/cAMP method.
Buffer:
Lyophilized from a 0.2 um filtered solution of 10mM HAc-NaAc, 150mM NaCl, 5% Mannitol, pH 4.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
Tag Free
NCBI Gene ID #:
5741
NCBI Official Name:
parathyroid hormone
NCBI Official Symbol:
PTH
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
9 kD
Protein Accession #:
P01270
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P01270