Myelin Oligodendrocyte Glycoprotein Recombinant Protein

Product Code: PSI-91-041

Supplier: ProSci

Code	Size	Price

PSI-91-041-0.05mg

0.05mg

£541.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Human

Storage:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Datasheet

Further Information

Additional Names:

Myelin-Oligodendrocyte Glycoprotein, MOG

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.

Biological Activity:

Tested for capability to induce EAE in rodents and monkeys

Buffer:

Lyophilized from a 0.2 um filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Fusion Tag:

C-6 His tag

NCBI Gene ID #:

4340

NCBI Official Name:

myelin oligodendrocyte glycoprotein

NCBI Official Symbol:

MOG

NCBI Organism:

Homo sapiens

Physical State:

Lyophilized

Predicted Molecular Weight:

15.2 kD

Protein Accession #:

Q16653

Protein GI Number:

767928039

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

E. coli

Swissprot #:

Q16653