Carbonic Anhydrase 8 Recombinant Protein

ProSci
Product Code: PSI-91-095
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-91-095-0.05mg0.05mg£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
Carbonic Anhydrase-Related Protein, CARP, Carbonic Anhydrase VIII, CA-VIII, CA8, CALS
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Carbonic Anhydrase 8 (CA8) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Because CA8 has some sequence similarity with other known carbonic anhydrase genes, it was firstly called as CA-related protein. Nevertheless, CA8 does not have a carbonic anhydrase catalytic activity. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3), which is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 500mM NaCl, 1mM DTT, pH 8.5 . It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
767
NCBI Official Name:
carbonic anhydrase 8
NCBI Official Symbol:
CA8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
34.04 kD
Protein Accession #:
P35219
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P35219