PIN Recombinant Protein

Product Code: PSI-91-198

Supplier: ProSci

Code	Size	Price

PSI-91-198-0.05mg

0.05mg

£838.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Human

Storage:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

Documents

Datasheet

Further Information

Additional Names:

Dynein Light Chain 1 Cytoplasmic, 8 kDa Dynein Light Chain, DLC8, Dynein Light Chain LC8-Type 1, Protein Inhibitor of Neuronal Nitric Oxide Synthase, PIN, DYNLL1, DLC1, DNCL1, DNCLC1, HDLC1

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain.

Buffer:

Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 200mM NaCl, 1mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Fusion Tag:

N-6 His tag

NCBI Gene ID #:

8655

NCBI Official Name:

dynein light chain LC8-type 1

NCBI Official Symbol:

DYNLL1

NCBI Organism:

Homo sapiens

Physical State:

Lyophilized

Predicted Molecular Weight:

12.5 kD

Protein Accession #:

P63167

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

E. coli

Swissprot #:

P63167