PPC-DC Recombinant Protein
| Code | Size | Price |
|---|
| PSI-91-232-0.05mg | 0.05mg | £883.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
Phosphopantothenoylcysteine Decarboxylase, PPC-DC, PPCDC, COAC
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Phosphopantothenoylcysteine Decarboxylase (PPC-DC) is an essential enzyme in the biosynthesis ofCoenzyme A and catalyzes the decarboxylation of PPC to Phosphopantetheine. PPC-DC catalyzes the decarboxylation of the Cysteine moiety of 4-Phosphopantothenoylcysteine (PPC) to form 4-Phosphopantetheine (PPantSH), this reaction forms part of the biosynthesis of Coenzyme A. The enzyme is a member of the larger family of Cysteine Decarboxylases including the Lantibiotic-Biosynthesizing enzymes EpiD and MrsD, all of which use a tightly bound Flavin cofactor to oxidize the Thiol moiety of the substrate to a Thioaldehyde.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 50mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
60490
NCBI Official Name:
phosphopantothenoylcysteine decarboxylase
NCBI Official Symbol:
PPCDC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
24.6 kD
Protein Accession #:
Q96CD2
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q96CD2