Protein Disulfide-Isomerase A6 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-91-476-0.05mg | 0.05mg | £673.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
Protein Disulfide-Isomerase A6, Endoplasmic Reticulum Protein 5, ER Protein 5, ERp5, Protein Disulfide Isomerase P5, Thioredoxin Domain-Containing Protein 7, PDIA6, P5, TXNDC7
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. The PDIA6 expressed in platelets, its functions as a chaperone that inhibits aggregation of misfolded proteins. PDIA6 is part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1. PDIA6 also plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
10130
NCBI Official Name:
protein disulfide isomerase family A member 6
NCBI Official Symbol:
PDIA6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
47.2 kD
Protein Accession #:
Q15084
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q15084