Carboxypeptidase A1 Recombinant Protein

Product Code: PSI-91-528

Supplier: ProSci

Code	Size	Price

PSI-91-528-0.05mg

0.05mg

£883.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Human

Storage:

Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Datasheet

Further Information

Additional Names:

Carboxypeptidase A1, CPA1, CPA

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Carboxypeptidase A1 (CPA1) is secreted as a pancreatic peptidase that comes from the precursor form of inactive procarboxypeptidase. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. It has a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 cleaves the C-terminal amide or ester bond of peptides and involves in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E.

Buffer:

Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mm NaCl, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Fusion Tag:

C-6 His tag

NCBI Gene ID #:

1357

NCBI Official Name:

carboxypeptidase A1

NCBI Official Symbol:

CPA1

NCBI Organism:

Homo sapiens

Physical State:

Liquid

Predicted Molecular Weight:

46.57 kD

Protein Accession #:

P15085

Protein GI Number:

20149322

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

Human Cells

Swissprot #:

P15085