Inositol Monophosphatase 2 Recombinant Protein

Product Code: PSI-91-990

Supplier: ProSci

Code	Size	Price

PSI-91-990-0.05mg

0.05mg

£883.00

Quantity:

Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO

Target Species: Human

Storage:

Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Datasheet

Further Information

Additional Names:

Inositol Monophosphatase 2, IMP 2, IMPase 2, Inositol-1(or 4)-Monophosphatase 2, Myo-Inositol Monophosphatase A2, IMPA2, IMP.18P

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.

Buffer:

Supplied as a 0.2 um filtered solution of 20mM Tris, 2mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Fusion Tag:

N-6 His tag

NCBI Gene ID #:

3613

NCBI Official Name:

inositol monophosphatase 2

NCBI Official Symbol:

IMPA2

NCBI Organism:

Homo sapiens

Physical State:

Liquid

Predicted Molecular Weight:

33.5 kD

Protein Accession #:

O14732

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

E. coli

Swissprot #:

O14732