Deoxycytidine Kinase Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-064-0.05mg | 0.05mg | £673.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Documents
Further Information
Additional Names:
Deoxycytidine Kinase, dCK
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His, T7 tag
NCBI Gene ID #:
1633
NCBI Official Name:
deoxycytidine kinase
NCBI Official Symbol:
DCK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
34 kD
Protein Accession #:
P27707
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P27707