Protein disulfide-isomerase A3 Recombinant Protein

ProSci
Product Code: PSI-91-869
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-91-869-0.05mg0.05mg£883.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Documents

Further Information

Additional Names:
PDIA3 protein, Protein disulfide-isomerase A3, 58 kDa glucose-regulated protein, Disulfide isomerase ER-60, ER protein 57, PDIA3
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol,pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
281803
NCBI Official Name:
protein disulfide isomerase family A member 3
NCBI Official Symbol:
PDIA3
NCBI Organism:
Bos taurus
Physical State:
Liquid
Predicted Molecular Weight:
55.3 kD
Protein Accession #:
A5D7E8
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
A5D7E8